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Why isn’t there a recommendation to give pneumococcal polysaccharide vaccine (PPV23) boosters to high-risk individuals every 5 years? Is it because of severe local reactions?

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Why isn’t there a recommendation to give pneumococcal polysaccharide vaccine (PPV23) boosters to high-risk individuals every 5 years? Is it because of severe local reactions?

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No. Ongoing booster doses are not recommended because pneumococcal polysaccharide vaccine does not boost well. Current data do not indicate that administering multiple boosters of PPV23 provides any more protection than one dose followed by a one-time booster 5 years later.

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