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Why use the buprenorphine/naloxone sublingual tablet for the treatment of opioid dependence?

April 26, 2017buprenorphine dependence naloxone opioid sublingual tablet treatment

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Why use the buprenorphine/naloxone sublingual tablet for the treatment of opioid dependence?

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Buprenorphine is a partial opioid agonist that suppresses opioid withdrawal symptoms and cravings (for more information, see Evolution of Opioid Dependence Treatment ). Naloxone is an opioid antagonist that is included to help deter diversion and misuse. When the buprenorphine/naloxone tablet is taken sublingually as prescribed, the naloxone is not absorbed into the bloodstream sufficiently to have any effect.