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Many patients with active lupus feel poorly in general and complain of fever, weight loss and tiredness. Patients with lupus also develop specific problems when the immune system attacks a particular organ(s) or area(s) in the body. Specific areas ... more
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Lupus is a condition that causes the body’s immune system to begin attacking healthy organs and tissue. The condition can cause a wide range of health problems, such as weakening joints, interfering with the function of kidneys, and even impairing ... more
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Author(s): Dooley MA Affiliation(s): Department of Medicine, Division of Rheumatology and Immunology, University of North Carolina at Chapel Hill, School of Medicine, USA. mary_dooley@med.unc.edu Publication date & source: 2006, Lupus., 15(3):179-82. ... more
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Discoid lupus erythematosus (DLE) is a chronic, disfiguring skin disease which is part of the LE (lupus erythematosus) spectrum of disease, which also includes systemic lupus erythematosus (SLE) and subacute cutaneous lupus (SCLE). It can also be a ... more
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Unfortunately, yes. A majority of people with lupus experience some hair loss (alopecia, pronounced al-o-PE-she-uh), whether they have a form of lupus that affects several organs or a form that mainly affects the skin. Most of the time, though, ... more
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There are different types of skin irritation in lupus, but that is not the only sign, and a positive ANA is not necessarily an indicator of lupus. The most "popular" lupus rash, known as a malar rash, is a reddish, sometimes blistery, rash over the ... more
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Objective: Following recent reports that pathogenic murine anti-DNA antibodies bind to -actinin, it was obviously of interest to assess the ability of human pathogenic anti-double-stranded DNA (anti-dsDNA) antibodies to bind this antigen. Both ... more
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My sister-in-law has all three diseases. She has had lupus since 1999, renal failure and pulmonary fibrosis since 2006. She now weighs a small 59 pounds at 36 years old. Everywhere I research and every doctor I ask can not give me an honest answer. ... more
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Over 20 years 42 of 138 patients with systemic lupus erythematosus "died"--that is, suffered actual death or went into terminal renal failure, or both; data from 41 were available for analysis. In most patients the causes of death were multiple. ... more
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Hi, this was posted on our home page to help some of our patients that need support: Basic Lupus Facts "Typical" clinical features include: - Fever, fatigue, and weight loss - Arthritis involving multiple joints for several weeks - Butterfly-shaped ... more
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