Remove the Loose DirtSweep or vacuum away loose dirt from the vinyl weatherstripping. Wipe away leftover dirt as much as possible with a dry cloth.Prepare the Soap SolutionMix a small amount of dishwashing detergent with warm water to create a sudsy soap solution. Dip a cleaning cloth into the solution, wetting it thoroughly. Wring out the cloth until it is no longer dripping.Clean the WeatherstrippingWipe the vinyl weatherstripping with the soapy cloth, rubbing as necessary to soften and remove the paint. According to Airlite Choice, soap usually removes paint from vinyl.