Does Affymetrix offer arrays for studying gene regulation?
Affymetrix Whole Genome Tiling Arrays may be employed to study the DNA sequences bound by regulatory proteins, as well as to identify sites of histone and DNA modification. In this particular type of array, probes are tiled at an average resolution of 35 base pairs as measured from the central position of adjacent 25-mer oligos, leaving a gap of approximately 10bp between probes. For more information on some of the tiling arrays available, refer to the following pages: • GeneChip Human Tiling 2.0R Array Set • GeneChip Mouse Tiling 2.0R Array Set In addition, species specific Promoter GeneChips are also available. Similar to the tiling arrays, probes are tiled at an average resolution of 35 base pairs as measured from the central position of adjacent 25-mer oligos, leaving a gap of approximately 10 base pairs between probes. Each promoter region covers approximately 6 kb upstream through 2.5 kb downstream of 5′ transcription start sites. For more information on the promoter arrays, refe