I have heard that I can take a single daily dose of methimazole for my Graves disease. Is the same true for PTU?
At present, we do not have good evidence to support single daily administration of PTU for most patients with Graves’ disease. Where this has been attempted, the success rate has been suboptimal. See Efficacy of single daily dosage of methimazole vs. propylthiouracil in the induction of euthyroidism. Clin Endocrinol (Oxf). 2001 Mar;54(3):385-90.