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If I order a cyclized peptide containing Trp, is there a possibility that the Trp will get oxidized?

April 26, 2017containing oxidized peptide POSSIBILITY trp

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If I order a cyclized peptide containing Trp, is there a possibility that the Trp will get oxidized?

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Most of our cyclized peptides are oxidized while the Trp is still protected which insures the Trp remains in its reduced form. The peptide is purified after the cyclization, which eliminates any oxidized Trp. Oxidation of any of the peptide residues can be seen as a mass gain of 16 Amu.