Is C. Pneumoniae Present in Atherosclerotic Tissues?
Patients with coronary artery disease are significantly more likely to have serologic evidence of past infection with C. pneumoniae (2,3). Immune complexes containing C. pneumoniae lipopolysaccharide have also been associated with 42- and 98-kDa C. pneumoniae species-specific antigens (4). These associations have been confirmed and extended to carotid artery disease and cerebrovascular disease (5,6). Although the high prevalence of C. pneumoniae antibodies in the population leaves a very narrow window for demonstrating statistically significant differences between cases and controls, seroepidemiologic studies have shown a consistent association. C. pneumoniae antibodies have been associated with coronary heart disease (16 studies) and cerebrovascular disease (2 studies) in 17 of 18 published studies; most had an odds ratio of 2.0 or greater (6). Most were statistically significant, and the risk is independent of other atherosclerosis risk factors (i.e., hypercholesterolemia, cigarette
Related Questions
- Rather than going to the trouble of installing a Yagi antenna why not reposition the existing antenna so that it mounts horizontally rather than the present vertical?
- When remodeling, can I get vinyl windows to fit present openings withÂout costly modifications?
- Is C. Pneumoniae Present in Atherosclerotic Tissues?
