There is no caffeine in Vanilla, Banana Cream, Berry Cream, or Strawberry PediaSure drinks. Chocolate PediaSure drink is very low in caffeine. It contains approximately 3 mg caffeine in 8 fl oz. (In contrast, brewed coffee contains approximately 100 mg caffeine in 8 fl oz; carbonated beverages contain approximately 50 mg caffeine in 12 fl oz.