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Should recombinant human growth hormone therapy be used in short small for gestational age children?

April 26, 2017age gestational growth Hormone Human recombinant short small therapy Used

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Should recombinant human growth hormone therapy be used in short small for gestational age children?

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Short small for gestational age (SGA) children represent 20% of all children with short stature1 and therefore constitute a significant portion of the caseload in a growth clinic. The recent approval of recombinant human growth hormone (GH) for the treatment of short stature in SGA children by the European Union’s Committee on Proprietary Medicinal Products offers a new licensed therapeutic option. This article examines the role of GH therapy in short SGA children with particular reference to selection of patients, effectiveness, safety, and its potential metabolic implications.