HPSF purification produces salt-free oligos in high yields. Typical purity levels are about 70%, but no guarantee of purity is made. HPSF purity oligos can be used in any application where salt-free oligos are used, but a little extra purity is desired. QuickLC purification produces oligos at 85%+ purity levels. This is the same level of purification that HPLC delivers. QuickLC purification is a proprietary chromatographic purification technique that is available on select oligo types. Where QuickLC purification is available, it produces oligos at the same purity level as HPLC; with at least twice the yield to provide much more material for your use. HPLC purification uses reversed-phase or ion exchange HPLC columns to produce oligos with 85%+ purity levels. It is available for a wider range of oligo types than QuickLC purification. HPLC purity is equivalent to QuickLC purity levels.