Which patients with hypertension and atherosclerotic renal artery stenosis benefit from immediate intervention?
Author(s): Krijnen P, van Jaarsveld BC, Deinum J, Steyerberg EW, Habbema JD Affiliation(s): Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. p.krijnen@erasmusmc.nl Publication date & source: 2004-02, J Hum Hypertens., 18(2):91-6. Publication type: Clinical Trial; Randomized Controlled Trial The objective was to identify subgroups of patients with hypertension and atherosclerotic renal artery stenosis who may benefit from immediate intervention. In the DRASTIC study, patients with hypertension, significant atherosclerotic renal artery stenosis, and a normal or mildly impaired renal function were randomized between immediate balloon angioplasty (PTRA; n=56) and drug therapy followed by angioplasty after 3 months, if needed (Med-PTRA; n=50). In this secondary analysis of the data, changes in the renal function and blood pressure after 1 year were studied by analysis of covariance in the following subgroups: patients with positive ca
