Who Should Consider MEN1 Screening by Gene Testing?
Screening may be offered to persons with MEN1 or with features resembling it. Affected relatives of persons with MEN1 can be tested. Asymptomatic offspring, brothers, or sisters of a person with MEN1 were born with a 50 percent chance of having inherited the gene; they too can be offered gene testing. While gene testing for certain genes can be definitive at any age, it is usually not offered to children below age 18 unless the test outcome would have an important effect on their medical treatment. Since treatable tumors occasionally begin by age 5 in MEN1, gene testing and tumor surveillance can begin at age 5.
