Why do Neutralizing Antibodies develop?
As part of the immune system, our body is able to distinguish between what is made internally and what is introduced, such as viruses or medication. In the case of medication molecules there is a potential for the body to recognize the medication molecule as a foreign rather than something that is made by your body. Whether or not you develop neutralizing antibodies to the medication is dependent upon your body and the molecule you are taking. There are several factors that can influence why our body would recognize an interferon as being foreign to the body. Such factors may include the manufacturing process, route of delivery into the body, the dosing amount and the frequency of dose of the interferon. If your body suspects that the medication is foreign, it may start to make neutralizing antibodies to fight it and prevent the medication from reaching its target.