Why is the BNFs dose of colchicine for acute gout different from that in the product literature?
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The BNF reflects the advice in the British Society for Rheumatology and British Health Professionals in Rheumatology Guideline for the Management of Gout (2007) and further expert advice that for the treatment of acute gout, colchicine should be given no more frequently than 2–4 times daily. This dose is preferred to the licensed dose of every 2–3 hours because, while remaining effective, it is less likely to cause side-effects.
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