Why was the Estrogen-Alone study stopped?
• After nearly 7 years of follow-up, study results show that CEE does not appear to affect the risk of heart disease. • At the same time, CEE appears to increase the risk of stroke, a clear risk. • CEE does not appear to increase the risk of breast cancer. • The National Institutes of Health (NIH) believes that enough data have been obtained in this study to provide an overall assessment of the risks and benefits of CEE and that these findings are not likely to change if the Estrogen-Alone study were continued for another year. • The NIH believes that an increased risk of stroke is not acceptable in healthy women in a research study, especially if CEE does not prevent heart disease.