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Your HuSH product is stated to be “locus-specific”. How do I know that it will knock down the expression of my variant or isoform?

April 26, 2017expression HuSH isoform knock Product variant

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Your HuSH product is stated to be “locus-specific”. How do I know that it will knock down the expression of my variant or isoform?

2 Answers

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Unless stated otherwise, shRNA constructs were designed to be effective against most transcriptional variants at a particular gene locus. If you would like a knockdown construct against a specific transcriptional variant(s), OriGene can generate a custom HuSH product that will selectively knockdown only the specified variants. Please review the options on our ExactshRNA website at www.origene.com/rnai/exactshRNA.

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Unless stated otherwise, shRNA constructs were designed to be effective against most transcriptional variants at a particular gene locus. If you would like a knockdown construct against a specific transcriptional variant(s), OriGene can generate a custom HuSH product that will selectively knockdown only the specified variants.