Abstract 2071: Can Increased Myocardial Contractility During Dobutamine Infusion Be Reliably Measured By Speckle Tracking?
Introduction: Speckle tracking is emerging as a useful adjunct in the evaluation of myocardial function, both at rest and during stress. We assessed the hypothesis that a novel software package incorporating such technology could document the inotropic effect of dobutamine, during different stages of a stress echo. Methods: We included 25 patients with a low pre-test probability of coronary artery disease, who were referred for dobutamine stress echo (DSE) and who had normal tests. Standard stress protocol images were taken at baseline (0µgm/kg/min), low dose (10µg/kg/min), intermediate (30µg/kg/min) and peak (40µg/kg/min). The standard images were reported by an experienced operator and the speckle analysis was done by a blinded independant observer. Mean radial strain and standard deviation (SD) were calculated for each coronary territory at each stage. Results: At baseline mean strain in the left anterior descending was 25.4%(SD 9.1). This increased to 31.7%(10) at low dose, 57%(20)
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