According to the RFA, Pioneer Awards are meant to support investigators who intend to pursue new research directions. Can you clarify what is meant by “new research direction?
A new research direction is one that is distinct from any research currently or previously conducted by the applicant or by other investigators. Successful Pioneer Award applicants are expected to propose highly innovative, and possibly risky, approaches to address or solve exceptionally important problems in biomedical or behavioral sciences. While a new research direction may have as its foundation the applicant’s prior work and expertise, it cannot simply be an obvious extension or scaling up of a research enterprise. Rather, a new research direction must reflect a fundamental new insight into the solution of a problem, which may derive from the development of exceptionally innovative approaches and/or from the posing of radically unconventional hypotheses.
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