Are images geocoded with datum and projection so I can use them in my GIS or CAD software?
Yes. When you open an image, the Image Web Server informs the client what datum (for example NAD83) and projection (for example NUTM11) that the image is in. This means you can use imagery, served directly from an Image Web Server, in your GIS, CAD or other software, and combine it with vectors and so forth.