Are there negative effects of calorie reduction in humans?
Even in light of all this research, there is no consensus about the overall effects of calorie reduction on humans in terms of illness or longevity. There are no universally accepted biomarkers of human ageing, so to use the results of animal studies to make predictions about human quality of life is risky. In addition, it is known that excessive fasting may lead to anemia, muscle wasting, dizziness, fatigue, nausea and depression, among other symptoms and conditions. Even the Calorie Restriction Society warns that a reduction in nutrition may lead to bone and muscle loss, increased cold sensitivity, disrupted menstrual cycles, reduced athletic performance and decreased sex drive. Therefore, any caloric restriction program must be undertaken with proper medical consultation. The study German researcher A.V. Whitte and his colleagues recruited 50 healthy elderly volunteers through newspaper ads with the intent of seeing whether dietary changes would affect memory and ability to learn. T
