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Can I filter aqueous solutions through a polytetrafluoroethylene (PTFE) hydrophobic membrane?

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Can I filter aqueous solutions through a polytetrafluoroethylene (PTFE) hydrophobic membrane?

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A. Yes you can, but the membrane requires pre-wetting with alcohol (like Isopropanol or Methanol) to establish flow with reasonable pressure differentials. We often use a 60/40 solution (60 Isopropanol/ 40 water) to prewet the membrane.

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