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Can one extrapolate manufactured nanoparticle toxicity using existing micro-particle and bulk toxicological databases?

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Can one extrapolate manufactured nanoparticle toxicity using existing micro-particle and bulk toxicological databases?

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• No, ability to extrapolate manufactured nanoparticle toxicity using existing particle and fibre toxicological databases are very limited. The toxicity of nanoparticles is influenced by the size and increases with decreasing particle size, on a mass for mass basis.

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