Can UGT1A1 Genotyping Reduce Morbidity and Mortality in Patients with Metastatic Colorectal Cancer Treated with Irinotecan?
Glenn Palomaki presented the status of the evidence report and the modeling, the summary manuscript, and the draft recommendation statement. The substantive changes made in the full evidence report in response to comments from peer reviewers were discussed. Based on the finalization of the report, work will continue on the draft manuscript and the draft recommendation statement. Report Update – Hereditary Nonpolyposis Colorectal Cancer (HNPCC) At the previous EWG meeting, Glenn Palomaki and EWG Technical Expert Panel members conducted a discussion on the AHRQ Evidence-based Practice Center (EPC) report commissioned by EGAPP and finalized by the Tufts EPC in May, 2007. This report, Hereditary Nonpolyposis Colorectal Cancer: Diagnostic Strategies and Their Implications is posted on the AHRQ website. The EWG has requested a supplemental evidence report to aid in their efforts to develop a clinical recommendation. The intent of the supplemental report is to update the evidence based on new
