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Do proteins delivered with BioPORTER reagent remain functionally active after delivery?

April 26, 2017active bioporter delivered DELIVERY Proteins Reagent remain

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Do proteins delivered with BioPORTER reagent remain functionally active after delivery?

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Yes, our data has shown that proteins do retain their biological activity after delivery with BioPORTER reagent. For example, caspase 3, caspase 8, and granzyme B retain the ability to induce apoptosis after BioPORTER-mediated delivery. Additionally, antibodies have retained their target specificity after delivery.