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Do the TSK_GEL PW/PWXL columns shed microparticles?

April 26, 2017columns microparticles pw pwxl shed

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Do the TSK_GEL PW/PWXL columns shed microparticles?

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Microparticles do not interfere with most detection methods used in HPLC. However, these particles can increase the noise level in laser light scattering detection systems. To minimize this effect using the PW/PWXL columns run the column overnight in 10-20% methanol at one-half the normal flow rate to clean any microparticles off the resin.