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Does continuous wear of silicone hydrogel lenses result in physiological changes?

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Does continuous wear of silicone hydrogel lenses result in physiological changes?

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Results from clinical trials indicate that the typical physiological changes associated with hypoxia from conventional extended wear of low Dk/t lenses do not occur with continuous wear of silicone hydrogel lenses. These changes include neovascularization, striae, microcysts and an increase in bulbar and limbal hyperemia.

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