Does fructose cause obesity?
Excess body fat occurs when people do not balance their energy (caloric) input with energy output. Extra calories may come from any caloric nutrient—proteins, fats, alcohol and carbohydrates including starches and sugars such as fructose. Lack of physical activity plays a significant role in promoting body fat accumulation and development of obesity. Some researchers have speculated that fructose may not be as satiating (produce feeling of fullness) as other carbohydrates because it does not stimulate insulin and leptin secretion nor suppress ghrelin production—all hormones that help to regulate hunger. However, it is important to note that this speculation is based on preliminary research which tested fructose levels at least three to four times higher than the average amount consumed by Americans. Furthermore, very few Americans ever consume fructose by itself, but rather in combination with glucose.