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Does the variable describing the half maximum saturation of lead apply to the absorbed dose of lead or the total lead intake?

April 26, 2017absorbed describing dose Half lead maximum saturation total

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Does the variable describing the half maximum saturation of lead apply to the absorbed dose of lead or the total lead intake?

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The IEUBK model first quantifies the fraction of each media-specific intake that is bioaccessible or available for absorption in the gut. Total intake is calculated as a function of two processes described as saturable and nonsaturable (passive and active uptake in the IEUBK Technical Support Document). The quantity of lead absorbed by the saturable pathway is a function of the total lead available in the gut, the fraction assumed to be absorbed via facilitated passive (PAF) diffusion, and the SATINTAKE variable, which is age-specific. Thus, the SATINTAKE variable applies to the intake that is available for absorption.