How Are Diabetes and Limb Amputation Connected?
Diabetics are unable to produce or properly use insulin – a hormone produced by the pancreas that unlocks the cells of the body, enabling glucose to enter and fuel them – so glucose accumulates in the blood. High glucose levels can damage the nerves of the feet, and impair the body’s ability to effectively fight infection. Reduced sensation resulting from nerve damage (known as diabetic or peripheral neuropathy) can interfere with the body’s ability to detect pain. Diabetes can damage blood vessels, leading to poor circulation in the extremities. Tiny abrasions, blisters, and cuts may become infected before they’re even noticed, and poor blood flow can hamper the body’s ability to heal. Left untreated, a minor foot injury could turn into a serious infection, possibly leading to gangrene (tissue death). If an infection turns into an ulcer that won’t respond to treatment, the toe or foot – or a portion of it – may eventually need to be amputated. An infection can sometimes persist post-s
