How are the mouse lines produced?
Different breeding schemes are used in the three mutagenesis facilities. Please visit the following websites at each mutagenesis facility for their breeding schemes. Northwestern University: http://genome.northwestern.edu/neuro/breeding_protocol.cfm The Jackson Laboratory: http://nmf.jax.org/protocols/genetics_scheme.html The Tennessee Mouse Genome Consortium: http://www.tnmouse.org/neuromutagenesis/mutagenesis.