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How do you complete the hepatitis A and heptatis B series with single-antigen vaccines if the patient started with Twinrix, and vice versa?

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How do you complete the hepatitis A and heptatis B series with single-antigen vaccines if the patient started with Twinrix, and vice versa?

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Because the hepatitis B component of Twinrix is equivalent to a standard, adult, dose of hepatitis B vaccine, the schedule is the same whether Twinrix or single-antigen hepatitis B vaccine is used. Single-antigen hepatitis A vaccine may be used to complete a series begun with Twinrix and vice versa. A person 19 years of age or older who receives one dose of Twinrix may complete the hepatitis A series with two doses of adult formulation hepatitis A vaccine separated by at least 5 months. A person who receives two doses of Twinrix may complete the hepatitis A series with one dose of adult formulation hepatitis A vaccine or Twinrix 5 months after the second dose. A person who begins the hepatitis A series with single-antigen hepatitis A vaccine may complete the series with two doses of Twinrix or one dose of adult formulation hepatitis A vaccine.

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