.There are basically two types of application: Fabric or other nonporous surfaces. For fabric decoration, the experts recommend a heat activated glue using your home iron. For all other applications, I think the best glue on the market is E6000. It can be goopy and odorous so use in a well ventilated area and protect the work surface. A tweezers for handling the crystals and a toothpick or other discardable applicator (cheapo paint brush like an eye liner size) will do the trick for applying the glue to such small items. You may also want to invest in a free-standing magnafying glass, one with a built in light, if you haven’t already done so. They are invaluable.