How Does Cymbalta Work?
Scientists are not exactly certain how Cymbalta helps makes patients with fibromyalgia feel better; fibromyalgia itself is poorly understood. Many believe the pain is due to changes in the nervous system which cause nerve cells to fire off too many signals. This makes a person overly sensitive to things that would normally not be painful. Researchers think that Cymbalta helps calm down these pain signals by increasing the level of two naturally occurring substances called serotonin and norepinephrine. These substances, which are found in the brain and other parts of the nervous system, can affect mood and are believed to help control and suppress feelings of pain. Cymbalta and other SNRIs block serotonin and norepinephrine from re-entering cells, and therefore increase the levels of the substances in the rest of the body. This process is thought to improve mood and relieve pain in patients with fibromyalgia.
