How does Forskolin help Depression?
Depression is believed to be due to an imbalance of neurotransmitters in the brain — most commonly either serotonergic (inhibitory) or dopaminergic (stimulatory). The response to various antidepressants depends on which neurotransmitter system has deviated farthest from the “norm.” If the serotonergic neurotransmitters are most deficient, serotonin precursors like 5-HTP or L-tryptophan, or the selective serotonin reuptake inhibitors (SSRI) like Paxil, Prozac, or Zoloft are most likely to be of help. If the dopaminergic (i.e., catecholamines like epinephrine or noradrenaline) neurotransmitters are deficient, catecholamine precursors like the amino acids L-Phenylalanine or L-Tyrosine, or monoamine oxidase inhibitors like GeroVital (GH3) or Deprenyl are most likely to help.