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How does heparin act as an anticoagulant?

ACT anticoagulant heparin
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How does heparin act as an anticoagulant?

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Unfractionated (UFH) and low molecular weight (LMW) heparin act by greatly enhancing the activity of plasma antithrombin, the major physiologic coagulation inhibitor. Clotting Factor IIa (thrombin) and Factor Xa are most sensitive to inactivation by heparin-antithrombin complexes.

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