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How does irradiation affect disease-causing microbes?

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How does irradiation affect disease-causing microbes?

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When microbes present in the food are irradiated, the energy from the rays is transferred to the water and other molecules in the microbe. The energy creates transient reactive chemicals that damage the DNA in the microbe, causing defects in the genetic instructions. Unless it can repair this damage, the microbe will die when it grows and tries to duplicate itself. Disease-causing organisms differ in their sensitivity to irradiation, depending on the size of their DNA, the rate at which they can repair damaged DNA, and other factors. It matters if the food is frozen or fresh, as it takes a higher dose to kill microbes in frozen foods. The size of the DNA “target” in the organism is a major factor. Parasites and insect pests, which have large amounts of DNA, are rapidly killed by extremely low doses of irradiation, with D-values of 0.1 kiloGray or less. It takes more irradiation to kill bacteria, because they have a somewhat smaller DNA, with D-values in the range of 0.3 to 0.

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When microbes present in the food are irradiated, the energy from the rays is transferred to the water and other molecules in the microbe. The energy creates transient reactive chemicals that damage the DNA in the microbe, causing defects in the genetic instructions. Unless it can repair this damage, the microbe will die when it grows and tries to duplicate itself. Disease-causing organisms differ in their sensitivity to irradiation, depending on the size of their DNA, the rate at which they can repair damaged DNA, and other factors. It matters if the food is frozen or fresh, as it takes a higher dose to kill microbes in frozen foods. The size of the DNA “target” in the organism is a major factor. Parasites and insect pests, which have large amounts of DNA, are rapidly killed by extremely low doses of irradiation, with D-values of 0.1 kiloGray or less. It takes more irradiation to kill bacteria, because they have a somewhat smaller DNA, with D-values in the range of 0.3 to 0.7 kiloGray

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