How does RFQMR work in Tissue Regeneration of the cartilage?
Like other tissues, bone and cartilage are constantly being built up and broken down by a variety of metabolic and physical influences. The major stimulus for bone and cartilage formation is a signal generated when these structures are subjected to tension or compression. This explains why bone atrophies in the absence of any significant pressure, such as weightlessness during space travel or immobilization in a cast. The transmission of this signal is also impaired following joint injury due to trauma or diseases such as osteoarthritis. QMR is designed to characterize and reproduce the required signal that initiates these regenerative activities by the induction of a spin in the hydrogen atoms thus creating a streaming potential in the extra cellular matrix (ECM) when bone or cartilage are placed under a load. In other words, when you take a step, putting weight on the joint, the cartilage is compressed, the fluid gets displaced, and it carries with it mobile ions, the sodium ions, le
