How does the ISRC determine if a conflict exists? If the ISRC finds that there is a conflict, what happens?
The ISRC reviews each financial disclosure in accordance with the University of California Guidelines for Disclosure and Review of Principal Investigators Financial Interest in Private Sponsors of Research (Academic Personnel Manual, Section 028-10 [http://www.ucop.edu/acadadv/acadpers/apm/apm-028.pdf). In brief, each case is reviewed on its on merits, with the facts and circumstances taken into consideration to determine the nature and extent of the conflict and the potential effect that conflict might have on the research. If a conflict of interest is found to exist, the ISRC will recommend actions to be taken to eliminate, reduce, or manage the conflict. For instance, depending on the seriousness of the conflict, the ISRC may simply recommend disclosing the interest in all publications and presentations, or they may recommend more stringent measures such as divestiture of all equity interest in the sponsor, prohibition of recruitment or enrollment of human subjects by the investigat