How is the information in IRIS developed?
EPA’s current process for developing IRIS information consists of: (1) an annual Federal Register announcement of EPA’s IRIS agenda and call for scientific information from the public on the selected chemical substances, (2) a search of the current literature, (3) development of health assessments and draft IRIS summaries, (4) peer review within EPA, (5) peer review outside EPA and solicitation of public comment, (6) EPA management review and approval, (7) preparation of final IRIS summaries and supporting documents, and (8) entry of summaries and supporting documents into the IRIS database.