How often should heart function be checked?
Pre and during chemotherapy (see 9.1.8.1.3., page 32 of the protocol) EURAMOS 1 patients require ECHO or MUGA pre doxorubicin (pre cycle 1) and beyond cumulative dose of 300mg/m2, ie pre cycle 5 and pre cycle 6. Anaesthetists may request an ECHO or MUGA pre surgery, ie post cycle 2. At the end and after chemotherapy (ee section 8.4.2., page 25 of the protocol) Also an ECHO or MUGA is required at the end of chemotherapy (ie post cycle 6) and (providing the end of treatment scan is normal) annually for minimum of 5 years [ Back To Questions ] Q.47 Patient started interferon in March 07. At the end of December 2007 the patient decided for social reasons to discontinue treatment with interferon. In May 2008 the patient requested to restart interferon and continue with the trial. Is this possible? Unfortunately, as termination of protocol treatment was because of patients preference, return to treatment cannot really be considered after such a long interruption.
