How to use LigBuilder wisely?
Good question! LigBuilder is a multiple-purposed structure-based drug design program. It provides the abilities for binding pocket analyzing, lead discovery and lead optimization. The modularized structure of LigBuilder enhances the flexibility in its application. Besides, it is very easy to use — the users like this so much. However, please remember: do not use it as a black box; use it as an idea generator for instead. At least at present drug design is not computer-done but computer-aided. Especially when analyzing the final results given by LigBuilder, we do believe that expertise is still very important. The major drawback of LigBuilder is that, sometimes, it gives molecules which are not synthetically feasible. In this case, you are encouraged to tailor those molecules if necessary.
