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How was Aspartame (Sugar Free Gold) tested before it was approved for use in foods?

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How was Aspartame (Sugar Free Gold) tested before it was approved for use in foods?

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Aspartame (Sugar Free Gold) is one of the most thoroughly studied ingredients in the food supply. It was tested in more than 100 scientific studies before the FDA approved it in 1981. The studies were conducted in laboratory animals and several subpopulations of humans, including healthy infants, children, and adults, lactating women, people with diabetes, obese individuals, and people who are carriers of the rare genetic disease phenylketonuria (PKU). Individuals with PKU cannot properly metabolize phenylalanine, one of Aspartames (Sugar Free Gold) components. After approval, extensive additional research was done. The results further confirmed the safety of Aspartame (Sugar Free Gold) for the general population.

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