How will CURE impact on management of ACS in a) the pre-hospital setting, and, b) the emergency room?
A. CURE indicates that clopidogrel should certainly be started as early as possible when patients present to hospital. We did not evaluate it in the pre-hospital setting, but given how easy it is to use, and it’s relative safety, I would recommend that in patients with unstable angina, future studies should evaluate it’s role in the pre-hospital setting. Perhaps even studies of acute myocardial infarction may wish to evaluate it in the pre-hospital setting.