How will the data will be handled when the memcached server is down?
The behavior is entirely application dependent. Most applications will fall back to loading the data from the database (just as if they were updating the memcached) information. If you are using multiple memcached servers, you may also want to remove a server from the list to prevent the missing server affecting performance. This is because the client will still attempt to communicate the memcached that corresponds to the key you are trying to load.