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How would sickle cell hydroxyurea therapy cause leukemia and/or lymphoma in patients?

April 26, 2017cause CELL hydroxyurea leukemia lymphoma Patients Sickle therapy

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How would sickle cell hydroxyurea therapy cause leukemia and/or lymphoma in patients?

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There has long been concern about the risk of hydroxyurea inducing leukemia due to its well-known (and utilized) effects on the bone marrow. However, modern studies/analysis suggest the real risk is minimal, if it even exists at all.