Theoretically, there is no reason why Bergamonte would have any interaction with warfarin. However, no research has been conducted in this area so Pure Health Direct recommends consulting your health care practitioner before taking Bergamot extract. From a theoretic and holistic viewpoint, the elevated rate of blood clotting found in people who have been prescribed warfarin is often a result in elevated, yet pre clinical inflammation processes. Since Bergamot extract is a natural anti-inflammatory it is expected that it would decrease this raised potential for blood clotting and support healthy, normal levels.