If a semen sample has a high percentage of sperm with fragmented DNA, is this condition permanent, or might it improve over time?
SCSA results are significantly more stable than results obtained by conventional semen analysis. However, a small percentage of men bordering on infertility may have relatively unstable DNA quality as assessed by the SCSA. These men may have poor fertility potential (>30% DFI) for a few months and then dramatically improve with pregnancy occurring during the month when SCSA data shows low levels of DNA fragmentation. Therefore, a second test is recommended in two to three months following poor SCSA results.
Related Questions
- If a semen sample has a high percentage of sperm with fragmented DNA, is this condition permanent, or might it improve over time?
- What is the best way of retrieving a DNA sample (i.e., blood, saliva, hair, semen). Does it all offer the same information?
- Can sperm with normal shape and motility have high levels of DNA fragmentation as assessed by the SCSA?
