In general, does fish oil affect LDL or HDL cholesterol?
Effects are on LDL and a smaller lipid fraction called chylomicrons. Clinical studies to address effects on HDL are ongoing. Further, it is reasonable to use high dose fish oil as an adjunct to standard statins like Zocor or Lipitor therapy. In this scenario, the goal is to reduce the statin therapy to absolutely the lowest dose possible, avoiding liver dysfunction due to long-term statin therapy and also the pain that high dose statins frequently cause (musculoskeletal morning pains.
