Is chloral hydrate/hydroxyzine a good option for paediatric dental outpatient sedation?
Author(s): Avalos-Arenas V, Moyao-Garcia D, Nava-Ocampo AA, Zayas-Carranza RE, Fragoso-Rios R Affiliation(s): Service of Paediatric Stomatology, Hospital Infantil de Mexico Federico Gomez, Mexico City. Publication date & source: 1998, Curr Med Res Opin., 14(4):219-26. Publication type: Clinical Trial; Randomized Controlled Trial The primary objective of this study was to evaluate in a random double-blind design, the sedative and behavioural responses of children undergoing outpatient paediatric dental procedures receiving either chloral hydrate (CH) alone or in combination with hydroxyzine. Forty American Society of Anaesthesiologists class I children (21 to 36 months of age) were randomly allocated to receive either 70 mg/kg CH alone or with 2 mg/kg hydroxyzine. The degree of crying, movement and overall behaviour was evaluated during treatment at different times. The combination of chloral hydrate/hydroxyzine (CH/H) significantly decreased crying and movement in relation to the effec
